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by DS Baldwin 2024 Cited by 305Many benzodiazepines (for example, diazepam) have longer- lasting active metabolites, which can accumulate with repeated dosing, especially in elderly patients Using the Equivalency Chart, switch to a longer acting agent by converting dose from short-acting agent. (alprazolam, lorazepam) to long-acting agents, such Benzodiazepine drug users often prefer short-acting, high-potency benzos, such as lorazepam or alprazolam, due to their fairly rapid and intense high. There are short-, intermediate-, and long-acting benzodiazepines However, our patient was prescribed lorazepam, which is metabolized to Lorazepam is a benzodiazepine. It is approved for the treatment of anxiety, insomnia, or sleep difficulty due to anxiety or stress. As is true of similar CNS-acting drugs, the decision as to when patients who have received injectable lorazepam, particularly on an outpatient basis, may again The half-life of Ativan is approximately 10 to 20 hours. Compared to short-acting benzos like Xanax (6 hours half-life) and long-acting benzos like Valium (21